In the season premiere episode, “Hella Duplicitous,” the FBI team hunts a dangerous enemy operative, and a deadly new foe emerges. Starring Sullivan Stapleton as Kurt Weller, Jaimie Alexander as Jane Doe / Remi, Rob Brown as Edgar Reade, Audrey Esparza as Tasha Zapata, Ashley Johnson as Patterson and Ennis Esmer as Rich DotCom. Guest Starring Rila Fukushima as Aiko, Mary Elizabeth Mastrantonio as Madeline Burke, Nyambi Nyambi as Dolan, Michael Bryan French as George Amherst, Aaron Abrams as Matthew Weitz and Tori Anderson as Blake Crawford
The series has revolved around a woman found naked in Times Square, her memory erased, her body covered in a series of coded tattoos. But as “Jane Doe” and the FBI team who discovered her work to decipher, investigate and solve the complex treasure map of her body, an ever-widening web of conspiracy and corruption is revealed, as is the truth behind Jane Doe’s real identity and the identity of the people who sent her to the FBI in the first place. But what does this nefarious group really want? And can Jane and her teammates stop them in time?