The night shift team of doctors and nurses at San Antonio Memorial’s emergency room are anything but ordinary. The risks they take to save lives straddle the line between heroic and impulsive, but are always worth it.
As season three concluded, the fate of the night shift was uncertain: Paul Cummings (Robert Bailey Jr.) led a staff walk-out after his father (guest star James McDaniel) bought the hospital and fired Topher Zia (Ken Leung). Overseas, TC Callahan (Eoin Macken) was left unconscious after a bombing on a refugee camp. Season four picks up just 48 hours later with the crew navigating the consequences of their decisions. In Syria, TC finds that suffering has no borders and channels his penchant for chaos into saving lives.
Back in Texas, Dr. Jordan Alexander (Jill Flint) takes charge to keep the ER running while treating more veterans and military personnel. Parenthood forces Drew Alister (Brendan Fehr) to re-evaluate his risk-taking behavior as an ER doctor and in the Army, while learning to raise a teenage daughter. Surgeon Scott Clemmens’ (Scott Wolf) personal life remains anything but easy, but that won’t stop him from diving headlong into his professional one. Paul must deal with the repercussions of standing up to his father, and pave his own way. His rival-turned-girlfriend Shannon Rivera (Tanaya Beatty) and charge nurse Kenny Fournette (JR Lemon) will soon learn three’s a crowd in a one-bedroom apartment.
In the season premiere, “Recoil,” Jordan and Drew perform a daring rescue by jumping from a chopper. Landing at the nearest VA hospital, Jordan sparks a plan to appease Julian (James McDaniel) and reunite her night shift team. Back at the hospital, Paul deals with the repercussions of standing up to his father while Scott dives headlong into his professional life. Kenny butts heads with Cain (recurring guest star Mark Consuelos), a traveling nurse with a mysterious past. Shannon indoctrinates Cain as they work in San Antonio Memorial's understaffed and overworked ER. Meanwhile, TC is held captive in Syria. In order to find Syd (recurring guest star Jennifer Beals), TC must treat his captor instead of returning to the safety of an air base with a civilian volunteer, Amira (Rana Roy).